What if the bacteria that live in our gut could be a way to fight aging? Theby from a young mouse in an old mouse, age-related inflammation in the retina and intestine of according to † It is not the first time that a of microbiota allows to “rejuvenate” mice.
The microbiota reduces age-related inflammation
In this case, the scientists first killed the microbiota of the recipient mice before giving them fecal pellets containing the microbiota of a younger or older mouse. They also analyzed markers of inflammation in the brain, retina and gut of transplanted mice. When a young mouse is inoculated with a microbiota from an older rodent, it shows an age-specific inflammation. Conversely, an old mouse, inoculated with the microbiota of a young animal, sees these properties take up again.
The implications of this research are still unclear, but scientists believe that:of the microbiota can prevent the inflammatory problems that occur with age. Research still needs to be done to determine the long-term benefits of on animal health and ultimately on human health.
Fecal transplant rejuvenates mice
Article bypublished on August 15, 2021
In mice, the transplantation of a fecal microbiota from a young mouse to an old mouse appears to “rejuvenate” certain abilities of the mouse.
About two kiloslive in our digestive system, according to the † By bacteria, and that affect our health, including our immune and neurological functions. A new study, published in proposes that this microbiome could be a relevant therapeutic target to promote healthy aging.
A finding of transplants offecal. The donors were mice, either 3 to 4 months old or 19 to 20 months old, while the recipients were systematically 19 to 20 months old. Only transplants from young mice had an effect. They have ” reverse aging differences on some aspects of immunity, the authors write, but they also have: cognitive impairments associated with aging.
All in due time
† Previous research […] have shown that thegut plays a key role in the and the aging process, recalls John Cryan, co-author of the study. This new research could be a game-changer, as we found that the microbiome could be used to reverse age-related brain deterioration. We also see evidence of improved learning ability and cognitive function. †
These results may have important implications for theor the by of aging. But he is” still early warns John Cryan, to project himself into therapies: Much more work is needed to see how these findings translate to humans. †